Scientists Develop LDL Cholesterol-Lowering Vaccine

A new virus-like particle-based vaccine leads to dramatic reductions in ‘bad’ LDL cholesterol in mice and macaques, says a team of scientists led by the University of New Mexico and NIH’s Lung and Blood Institute.

This image shows that high levels of active PCSK9 gene (green color) prevent LDL cholesterol (red color) from binding to the surface of liver cells. Image credit: Rockefeller University.
LDL (low-density lipoprotein) cholesterol, also known as ‘bad’ cholesterol, makes up the majority of the body’s cholesterol.
A high LDL cholesterol level is considered a risk factor for coronary artery disease because, under certain conditions, it can cause hardening of the arteries.
According to the CDC, 73.5 million adults (31.7%) in the United States have high LDL… Read more

New Study Explores How Storage on ISS May Affect Medications

According to a new study published in the AAPS Journal , medication degradation in space does not differ from what is seen on the planet.

The International Space Station is featured in this image photographed by an STS — 132 crew member on board the Space Shuttle Atlantis after the station and shuttle began their post-undocking relative separation. Undocking of the two spacecraft occurred on May 23, 2010. Image credit: NASA / Crew of STS — 132.
Current procedures ensure that medications aboard the International Space Station (ISS) are restocked before their expiration dates, but resupply may not be possible on future long-duration exploration missions.
Medications degrade over time, particularly with exposure to light, oxygen, or humidity; and degradation is h… Read more